Liverpool continue to march towards the title in a midweek which saw history made, as Amazon Prime aired their first ever round of Premier League matches.
Jose Mourinho returns to one of his former clubs as Manchester United meet Tottenham Hotspur in a blockbuster clash at Old Trafford.
Chelsea look to end their three match winless run in all competitions as they welcome Aston Villa to Stamford Bridge.
West Ham United look to make it consecutive wins in five days as they visit Wolves at Molineux.
Defending champions, Manchester City will begin their FA Cup title defence at home to Port Vale in the Third Round.
Liverpool continue to dominate the Premier League after a lively weekend of surprise results and a relegation six pointer.
Chelsea look to reignite their title challenge as they meet free-falling West Ham in a mouth-watering London derby.
Liverpool continue their march towards the Premier League title on a crazy weekend, which saw Jose Mourinho’s return plus a thriller at Bramall Lane.
Aston Villa look to move away from the relegation zone as they welcome Newcastle United to Villa Park in Monday Night Football.
Arsenal look to begin a turnaround in form as they take on Southampton at the Emirates Stadium.