Relegation battling Cardiff face a tough trip to Craven Cottage as they face Fulham in a pivotal match.
Crystal Palace welcome Everton to Selhurst Park as the Toffees continue their search for a top seven Premier League finish.
Tottenham Hotspur can take a huge step towards securing another top four finish as they welcome West Ham United to the Tottenham Hotspur Stadium.
Title chasing Liverpool welcome Huddersfield to Anfield in a crucial clash for the Reds’ title hopes as this weekend’s Premier League action kicks off with Friday Night Football.
Manchester City have returned to the league summit after a dramatic week of Premier League action, as various battles continue to twist and turn.
Wolverhampton Wanderers welcome Arsenal to Molineux in a rearranged Premier League clash, as both teams fight for places in Europe next season.
Manchester United welcome Manchester City to Old Trafford for a pivotal Manchester derby, which could define this season’s Premier League.
Tottenham Hotspur welcome Brighton & Hove Albion to the Tottenham Hotspur Stadium for a decisive Premier League clash affecting both ends of the table.
Watford welcome Southampton to Vicarage Road for a huge Premier League clash affecting the Europe and relegation battles.
Chelsea welcome Burnley to Stamford Bridge for a dose of Easter Monday Night Football as this weekend’s Premier League action draws to a close.