Brighton are looking to reach the last eight for second consecutive season whilst Derby have lost their last four appearances at this stage, yet have already knocked out two Premier League teams in both cups this season.
This weekend’s Fifth Round action from FA Cup gets underway at Loftus Road as QPR aim to cause a cupset and dump Premier League’s Watford out.
With seven out of eight FA Cup ties now sorted, West Bromwich Albion meet Brighton & Hove Albion in the last fourth round replay.
This midweek sees the FA Cup take centre stage as five fourth round ties remain still to be settled, with Tuesday’s big match seeing Newport host Middlesbrough at Rodney Parade.
Without a doubt is this the biggest tie from the draw as last season’s finalists will meet at Stamford Bridge in a massive clash.
70 places currently separate these Bees in the football pyramid, so which set of fans will be buzzing come full time in what promises to be an entertaining battle?
After Carabao Cup semi-final heartbreak in midweek, Tottenham visit Crystal Palace at Selhurst Park looking to book their place in fifth round draw in Sunday’s big match.
With Bristol City and Manchester United already through, 22 teams aim to join them in the next round of FA Cup.
This weekend’s FA Cup fourth round action gets underway with a huge clash at the Emirates Stadium as Arsenal meet last season’s beaten finalists, Manchester United.
Southampton welcome Derby County to St Marys for the final FA Cup Third Round replay.