Arsenal look to end a nine match winless run in all competitions as they visit West Ham United at the London Stadium in Monday Night Football.
West Bromwich Albion look to return to the Championship summit as they welcome Swansea City to The Hawthorns.
Brighton welcome Wolves to the Amex Stadium in the climax to this weekend’s Super Sunday.
Aston Villa kicks off this weekend’s Super Sunday as they welcome title chasing Leicester City to Villa Park.
Southampton look to continue their improved form as they visit Newcastle United at St James’ Park.
After suffering defeats in midweek, Norwich City and Sheffield United look to get their seasons back on track as last season’s top two Championship teams meet at Carrow Road.
Luton Town welcome Wigan Athletic to Kenilworth Road in a Sky Bet Championship relegation six pointer.
Manchester City welcome local rivals, Manchester United to the Etihad Stadium for the first Manchester derby of the season.
Managerless and relegation battling Watford welcome Crystal Palace to Vicarage Road, as the Eagles continue their hunt for a fifth-placed finish.
After suffering their first defeat under Jose Mourinho in midweek, Tottenham Hotspur look to hit back as they welcome a shaky Burnley to the Tottenham Hotspur Stadium.