Four points separate both sides as they look to bounce back from blowing leads at the weekend, making three points vital to their hopes of automatic promotion.
Sheffield United will be without defender, Chris Basham, who is banned after collecting his 10th yellow card of season at weekend.
Marvin Johnson meanwhile is ineligible to face his parent club so expect changes to the Blades’ lineup.
Middlesbrough have a full squad available although Lewis Wing is a doubt after limping off against Leeds with a groin strain.
This has all the ingredients for a cracker because both sides will be expected to hit back from a defensive drop off in dying stages of their games against Aston Villa and Leeds.
Throw in the pressure of a promotion race which the Blades drifted away from last season whilst Boro rose, then there will certainly be goals in this but am going for a thrilling draw.
Prediction: Sheffield United 2-2 Middlesbrough
Result: Sheffield United 1-0 Middlesbrough