The winner of this tie will be rewarded with a home clash against Derby County in fifth round and a step closer towards Wembley.
West Brom are set to make changes with Sam Field and Rekeem Harper amongst those set to start.
Matt Phillips is ruled out with an ankle injury whilst James Morrison could miss out with a similar issue, if he fails a late fitness test.
Brighton face the possibility of having Dale Stephens unavailable due to a hip injury he picked up during weekend’s goalless draw against Watford.
Jose Izquierdo is definitely sidelined with a knee injury as Chris Houghton prepares to rotate his Seagulls.
Given their dire away form, Brighton really ought to of won this at home but this is a chance to start finding some momentum on the road.
As for West Brom, they need to hit back after losing from a winning position at home for the first time this season.
I am therefore expecting an edgy game here but have a feeling that West Brom will just edge this.
Prediction: West Bromwich Albion 1-0 Brighton & Hove Albion