70 places currently separate these Bees in the football pyramid, so which set of fans will be buzzing come full time in what promises to be an entertaining battle?
Barnet will be without goalkeeper, Mark Cousins as he serves a one match ban following his red card against Braintree last weekend.
Rihards Matrevics will therefore make his first start in place of Cousins, having signed from West Ham in the summer.
Brentford remain without Emiliano Marcondes (ankle) and Lewis MacLeod (hamstring) but changes will be made.
Barnet have enjoyed a great run and proved more than a match for Sheffield United in last round.
Brentford however are a solid side who are back to their best after an autumn wobble, making them my tip to secure what should be easy yet comfortable passage to the fifth round.
Prediction: Barnet 0-3 Brentford
Result: Barnet 3-3 Brentford