Manchester City however will be tough opposition after progressing from each of their last three appearances at this stage en route to lifting the trophy in each of those seasons.
Manchester City have a near full squad to choose from with no fresh injury concerns.
Left-back, Benjamin Mendy is back training but won’t be available for selection until early February. Goalkeeper, Claudio Bravo is a long-term absentee with an Achilles rupture.
Burton will hand Stephen Quinn and John Brayford late fitness tests ahead of this match.
Scott Fraser and Jamie Allen are also available for the Brewers.
Burton’s best hope here will be to replicate what Bristol City did this time last season at the Etihad and avoid losing by more than two goals.
City however gave Rotherham a beating at weekend and despite various squad rotation, I fancy them to produce something similar and put this leg beyond the Brewers.
Prediction: Manchester City 5-0 Burton Albion
Result: Manchester City 9-0 Burton Albion