Ainsley Maitland-Niles flicked in Alex Iwobi’s cross to open the scoring for Arsenal after 11 minutes. Roberto Firmino then swiftly turned the game on its head minutes later with a quick-fire double to put Liverpool ahead.
Mane then added the Reds’ third with a close range volley before Mohamed Salah was fouled near the goaline by Sokratis Papastathopoulos on stroke of half-time. Up stepped the Egyptian to fire down the middle to hand Liverpool a 4-1 lead at break.
Both teams then had chances in second half to score until Sead Kolasanic pushed Dejan Lovren during a corner to concede a penalty.Embed from Getty Images
Firmino put the spot-kick down middle to seal his hat-trick and a 5-1 home win as Liverpool made it an entire calendar year unbeaten at home.
That result means that Liverpool are now seven points clear of Manchester City who saw off Southampton 3-1 to leapfrog Tottenham into second, following their shock home defeat by Wolverhampton Wanderers.
Harry Kane initially handed Spurs a first half lead after bending a screamer into left hand corner. Wolves however struck back late on when Willy Boly headed in from a corner before Raul Jimenez and Helder Costa then struck in dying minutes, handing Wolves a 3-1 away win.
Arsenal meanwhile remain fifth but five points behind Chelsea after N’Golo Kante handed the Blues victory over Crystal Palace.Embed from Getty Images
Down at bottom, Fulham saw off bottom-placed Huddersfield through Aleksandar Mitrovic’s late strike to move four points closer to safety.
Burnley also collected a win after beating West Ham through first-half goals from Chris Wood and Dwight McNeil to move level on points with Southampton, but remain in relegation zone on goal difference.
Cardiff managed to leapfrog the Saints into 16th after snatching their first away win of season at Leicester through Victor Camarasa’s last gasp blast into top right corner beyond Kasper Schmeichel.Embed from Getty Images
Elsewhere, Manchester United made it three straight wins under Ole Gunnar Solskjaer by beating Bournemouth 4-1 to remain sixth and move eight points behind fourth-placed Chelsea.
Paul Pogba’s brace and Marcus Rashford’s poke in from crosses had United in control at half-time, despite Nathan Ake’s stoppage time header briefly offering Bournemouth hope of a comeback. That hope was however faint as Romelu Lukaku sealed the three points with a flick in midway through second half.
Finally, Brighton beat Everton through Jurgen Locadia’s tap in from a corner whilst Watford were held to a 1-1 draw by Newcastle United.