After a thrilling Tuesday night full of Groups E-H action, its time for Groups A-D to take centre stage with Tottenham and Liverpool at heart of big ties.
Atletico Madrid vs Club Brugge
Borussia Dortmund vs Monaco
Club Brugge did a solid job last time out to suffer a respectable defeat at Borussia Dortmund but Atletico Madrid will be tougher to keep quiet so can see another defeat here.
Monaco showed positive signs when attacking against Atletico but were defensively exposed at times, which will be something which Borussia Dortmund can ruthlessly punish if given chance.
I therefore can see a home win coming here for Dortmund but both teams should score.
Atletico Madrid 2-0 Club Brugge
Borussia Dortmund 2-1 Monaco
PSV vs Inter Milan
Tottenham Hotspur vs Barcelona
I am expecting a decent game at PSV because the Dutch side did give Barcelona a good go before eventually being ripped to shreds. Inter Milan however were lucky to pick up their win over Tottenham who went AWOL defensively.
At this stage of group, I am going to go for a draw because PSV are a decent side whilst Inter are still adjusting to the current European Football landscape.
Spurs meanwhile have a tough task in store as they welcome Barcelona to Wembley for a huge clash.
Both sides have spent the last fortnight in contrasting form with Barca struggling domestically whilst Tottenham have won all of their games, which adds further intrigue to how this game could play out.
Throw in numerous omens like Mauricio Pochettino previously only winning one match as a manager against Barcelona and Barca winning just one of last seven Champions League away games, and a draw could be likely here.
PSV 1-1 Inter Milan
Tottenham Hotspur 2-2 Barcelona
PSG vs Red Star Belgrade (5:55pm)
Napoli vs LiverpoolEmbed from Getty Images
PSG should easily ease past Red Star Belgrade if play like they did in their defeat at Anfield, without any doubt.
Liverpool meanwhile face an interesting game as Carlo Ancelotti comes face to face with Hungarian referee – Viktor Kassai, who cost his Bayern Munich a semi-final spot in 2016-17 edition of this competition.
Ancelotti teams are often expressive and direct but this Liverpool side are fierce when attacking and particularly down the flanks, which could be key here.
We should see a good game here but I can see Liverpool eventually running out comfortable winners once settled.
PSG 3-0 Red Star Belgrade
Napoli 0-2 Liverpool
Lokomotiv Moscow vs Schalke (5:55pm)
Porto vs Galatarasay
After a 3-0 thrashing by Galatarasay, Lokomotiv really need to beat Schalke who were solid if unspectacular against Porto last time out.
With CSKA Moscow having beaten Real Madrid already this week, their victory will give Lokomotiv some extra belief in making it two Moscow home wins within 24 hours so I am backing them to just have edge here.
Porto meanwhile need to pull up their socks and deliver a strong performance otherwise Galatarasay will certainly dish out similar treatment that Lokomotiv got last time out.
Lokomotiv Moscow 1-0 Schalke
Porto 1-2 Galatarasay