Sunday’s FA Cup quarter final action kicks off at the DW Stadium as Mark Hughes takes his first Southampton match, away at Wigan Athletic.
Wigan are without Nick Powell after the midfielder limped off with a hamstring injury during Wednesday’s league win at Bradford City.
Devante Cole, Donervon Daniels and James Vaughan are all cup-tied.
Southampton are without the injured pair of Charlie Austin and Steven Davis as they recover from hamstring injuries.
Japanese defender, Maya Yoshida could return to the lineup after seven weeks on sidelines with a knee injury.
Wigan come into this match with just two defeats in 23 matches since a home defeat to Bradford City on 18th November.
After taking a 2-2 draw at Bournemouth in third round to earn a replay, the Latics have won their last three FA Cup games at home.
Southampton come into this match after sacking Mauricio Pellegrino following a disastrous run of form with just one win since mid November.
That is just one of four away wins this season in all competitions and haven’t scored in.
Wigan will be tough opposition because they know how to beat top flight sides at home.
I however see Southampton having that more desire due to a change of manager and nicking this in extra time.
Prediction: Wigan Athletic 1-2 Southampton AET
Result: Wigan Athletic 0-2 Southampton (after normal time)