After the relegation battle dominated Saturday, attention turns to the battle for Europe with Manchester United and Liverpool both in action.
Both face teams near the bottom but almost certain to remain in the Premier League.
Burnley vs Manchester United
With a defensive crisis and Zlatan Ibrahimovic out injured, this is a tough trip to Turf Moor for Jose Mourinho and his Red Devils.
To compound their misery, United have scored just one goal in their last four league clashes at Turf Moor.
The last goal came back in 1976 and is just one of two wins away at Burnley in their last 12 visits in top division.
The Clarets have however seemed to slow down with just one win since the end of January.
Could victory here reignite their winning desire and continue their impressive home record this season?
Man Utd are unbeaten in 22 league games but a draw here will equal their record for most draws in a season, which is 13 set in 1998-99.
Mourinho however has a tight yet brutal run in with Manchester City, Arsenal and Tottenham all to come along with the Europa League semis against Celta Vigo.
Throw in an defensive crisis and Ibrahimović’s injury ruling him out for rest of season then an upset could be simmering away.
With Marcus Rashford in strong form, the visitors should get something here but only Manchester City, Tottenham and Arsenal have come away from Burnley with wins.
A draw here is likely but with United probably keen to avoid further injuries, expect them to play tentatively and gift Burnley the three points.
Prediction: Burnley 2-1 Manchester United
Result: Burnley 0-2 Manchester United
Liverpool vs Crystal Palace
Crystal Palace will be hoping to claim another top scalp this month after dismantling Chelsea, three weeks ago.
Liverpool has an defensive concern after three key players in the back line were unable to train this weekend.
Crystal Palace themselves are without Mamadou Sakho, who is unavailable against his parent club.
Palace have won on their last two trips to Anfield and with both sides in similar form, expect a proper duel here. No team has won three away games at Anfield on the bounce since Chelsea in October 2005.
Eagle, Christian Benteke will have a point to prove here so expect Jurgen Klopp to set up his side to shut the Belgian out.
If they can prevent Wilfried Zaha and Andros Townsend from getting the ball to Benteke then victory will be the Reds.
This will be open and competitive but Liverpool should pull through here with ease.
Prediction: Liverpool 2-0 Crystal Palace
Result: Liverpool 1-2 Crystal Palace